Brufen Cream (Ibuprofen)
COMPOSITION:
Each 100gms contain:
Ibuprofen (2-[4-isobutylphenyl] propionic acid) B.P. ............ 10gm.
PROPERTIES AND EFFECT
Brufen (Ibuprofen) has analgesic and anti-inflammatory properties. Clinical studies have shown that Brufen Cream works as an
anti-inflammatory and analgesic in the treatment of traumatised or inflamed tissue. Brufen Cream is a proven anti-
inflammatory in animals with histamine or carrageenan induced inflammation.
Brufen Cream is well tolerated.
PHARMACOKINETIC
The absorption of Ibuprofen after topical use of Brufen Cream was less, but measurable blood concentrations were found.
The half-life – about 2 hours – guarantees fast elimination from the blood. As a result of this fast elimination of Ibuprofen
(almost complete elimination after 24 hours), there is no significant accumulation of Ibuprofen or it's metabolites in human
serum.
INDICATIONS
For local treatment of pain and inflammation:
– in various forms of soft tissue rheumatic disorders (myalgia, lumbago, shoulder/arm syndrome, tenovaginitis, torticollis,
neck stiffness.
– localised rheumatic symptoms (Arthroses of peripheral joints).
– in traumatically caused lesion, such as sporting injuries to the tendons, ligaments, muscles and joints.
– in phlebological conditions such as phlebitis and thrombophlebitis.
DOSAGE
For external use only.
Massage over the affected area two or three times daily.
Brufen Cream can also be prescribed alongwith Brufen 400/600 as a backup to the oral treatment.
It is contra-indicated in patients with hypersensitivity to the drug.
PRECAUTIONS
Hypersensitivity to Brufen Cream can occur. If this should happen, stop the treatment and continue with a suitable
replacement.
Brufen Cream should not come into contact with eyes, mucous membranes or open wounds.
PREGNANCY AND BREAST FEEDING
As a safety precaution, do not give Brufen Cream to pregnant mothers; though no malformations were found in animal
experiments. Traces of Ibuprofen to be found in the mother's milk are not really dangerous to the child.
STORAGE
Protectfrom heat&light.
HOW SUPPLIED
30g Tubes (10% Ibuprofen) in carton list No. N 409.
 |
| Brufen Cream (Ibuprofen) |
Brufen Cream (Ibuprofen)
COMPOSITION:
Each 100gms contain:
Ibuprofen (2-[4-isobutylphenyl] propionic acid) B.P. ............ 10gm.
PROPERTIES AND EFFECT
Brufen (Ibuprofen) has analgesic and anti-inflammatory properties. Clinical studies have shown that Brufen Cream works as an
anti-inflammatory and analgesic in the treatment of traumatised or inflamed tissue. Brufen Cream is a proven anti-
inflammatory in animals with histamine or carrageenan induced inflammation.
Brufen Cream is well tolerated.
PHARMACOKINETIC
The absorption of Ibuprofen after topical use of Brufen Cream was less, but measurable blood concentrations were found.
The half-life – about 2 hours – guarantees fast elimination from the blood. As a result of this fast elimination of Ibuprofen
(almost complete elimination after 24 hours), there is no significant accumulation of Ibuprofen or it's metabolites in human
serum.
INDICATIONS
For local treatment of pain and inflammation:
– in various forms of soft tissue rheumatic disorders (myalgia, lumbago, shoulder/arm syndrome, tenovaginitis, torticollis,
neck stiffness.
– localised rheumatic symptoms (Arthroses of peripheral joints).
– in traumatically caused lesion, such as sporting injuries to the tendons, ligaments, muscles and joints.
– in phlebological conditions such as phlebitis and thrombophlebitis.
DOSAGE
For external use only.
Massage over the affected area two or three times daily.
Brufen Cream can also be prescribed alongwith Brufen 400/600 as a backup to the oral treatment.
Brufen Cream (Ibuprofen)
CONTRA-INDICATIONSIt is contra-indicated in patients with hypersensitivity to the drug.
PRECAUTIONS
Hypersensitivity to Brufen Cream can occur. If this should happen, stop the treatment and continue with a suitable
replacement.
Brufen Cream should not come into contact with eyes, mucous membranes or open wounds.
PREGNANCY AND BREAST FEEDING
As a safety precaution, do not give Brufen Cream to pregnant mothers; though no malformations were found in animal
experiments. Traces of Ibuprofen to be found in the mother's milk are not really dangerous to the child.
STORAGE
Protectfrom heat&light.
HOW SUPPLIED
30g Tubes (10% Ibuprofen) in carton list No. N 409.
Brufen Cream (Ibuprofen)
Reviewed by Athar
on
07:46
Rating:
Reviewed by Athar
on
07:46
Rating:
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